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US08796209B2 Compositions and methods related to anti-FGF agents 有权
与抗FGF药物有关的组合物和方法

Compositions and methods related to anti-FGF agents
Abstract:
The invention relates to an isolated amino acid that can act as an antagonist to FGF signaling, comprising at least a portion of the FGF protein amino acid sequence, and including a mutation in either a) the integrin αvβ3 binding region of FGF-1; or b) the FGFR binding region of FGF-1.
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