Invention Grant
- Patent Title: Stable formulation of growth hormone comprising lactate anion
- Patent Title (中): 包含乳酸盐阴离子的生长激素的稳定配方
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Application No.: US12851295Application Date: 2010-08-05
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Publication No.: US08796210B2Publication Date: 2014-08-05
- Inventor: Jan Jezek
- Applicant: Jan Jezek
- Applicant Address: GB Cambridge
- Assignee: Arecor Limited
- Current Assignee: Arecor Limited
- Current Assignee Address: GB Cambridge
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Priority: GB0813004.9 20080716
- Main IPC: A61K38/27
- IPC: A61K38/27
Abstract:
An aqueous composition comprising a therapeutic protein further characterized in that (i) the pH of the composition is adjusted to be between about 5.9 and 6.3, preferably about 6.1; (ii) the composition comprises at least one displaced buffer having a pKa within 1 to 3 pH units of the pH of the composition; (iv) the osmolarity of the composition is between 150-500 mOsm/L.
Public/Granted literature
- US20110034898A1 Stable Formulation of a Therapeutic Protein Public/Granted day:2011-02-10
Information query
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