Invention Grant
US08796212B2 Composition and method for delivery of BMP-2 amplifier/co-activator for enhancement of osteogenesis
有权
用于递送BMP-2放大器/共活化剂以增强成骨的组合物和方法
- Patent Title: Composition and method for delivery of BMP-2 amplifier/co-activator for enhancement of osteogenesis
- Patent Title (中): 用于递送BMP-2放大器/共活化剂以增强成骨的组合物和方法
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Application No.: US13186165Application Date: 2011-07-19
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Publication No.: US08796212B2Publication Date: 2014-08-05
- Inventor: Paul O. Zamora , Brent Lee Atkinson , Xinhua Lin , Louis A. Pena
- Applicant: Paul O. Zamora , Brent Lee Atkinson , Xinhua Lin , Louis A. Pena
- Applicant Address: US MD Rockville
- Assignee: BioSurface Engineering Technologies, Inc.
- Current Assignee: BioSurface Engineering Technologies, Inc.
- Current Assignee Address: US MD Rockville
- Agency: Peacock Myers, P.C.
- Agent Janeen Vilven
- Main IPC: A61P19/08
- IPC: A61P19/08 ; A61K38/18 ; A61K38/08 ; A61K38/10 ; C07K14/51 ; C07K17/02 ; C07K17/14
Abstract:
A composition comprising a synthetic growth factor analog comprising a non-growth factor heparin binding region, a linker and a sequence that binds specifically to a cell surface receptor and an osteoconductive material where the synthetic growth factor analog is attached to and can be released from the osteoconductive material and is an amplifier/co-activator of osteoinduction.
Public/Granted literature
- US20110305741A1 Composition and Method for Delivery of BMP-2 Amplifier/Co-Activator for Enhancement of Osteogenesis Public/Granted day:2011-12-15
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