Invention Grant
- Patent Title: Feedback prodrug
- Patent Title (中): 反馈前药
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Application No.: US13222495Application Date: 2011-08-31
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Publication No.: US08796229B2Publication Date: 2014-08-05
- Inventor: Geert-Jan Boons , Jun Guo
- Applicant: Geert-Jan Boons , Jun Guo
- Applicant Address: US GA Athens
- Assignee: University of Georgia Research Foundation, Inc.
- Current Assignee: University of Georgia Research Foundation, Inc.
- Current Assignee Address: US GA Athens
- Agency: Mueting, Raasch & Gebhardt, P.A.
- Main IPC: A61K47/00
- IPC: A61K47/00 ; A61K47/48
Abstract:
Compounds and methods for use in selectively inhibiting a lytic enzyme based on feedback inhibition are described. The conjugated compound serves as a substrate for a lytic enzyme. Cleavage of the conjugated compound by the lytic enzyme releases an inhibitor of the enzyme.
Public/Granted literature
- US20120058960A1 FEEDBACK PRODRUG Public/Granted day:2012-03-08
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