Invention Grant
- Patent Title: Sirna compounds comprising terminal substitutions
- Patent Title (中): Sirna化合物包括末端取代
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Application No.: US13511111Application Date: 2010-11-25
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Publication No.: US08796239B2Publication Date: 2014-08-05
- Inventor: Sharon Avkin-Nachum
- Applicant: Sharon Avkin-Nachum
- Applicant Address: US CA Fremont
- Assignee: Quark Pharmaceuticals, Inc.
- Current Assignee: Quark Pharmaceuticals, Inc.
- Current Assignee Address: US CA Fremont
- Agency: Cooper & Dunham LLP
- Agent John P. White
- International Application: PCT/US2010/058123 WO 20101125
- International Announcement: WO2011/066475 WO 20110603
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12Q1/68
Abstract:
The invention relates to modified siRNA compounds which down-regulate target gene expression, to pharmaceutical compositions comprising such compounds and to methods of treating and/or preventing the incidence or severity of various diseases or conditions associated with the genes and/or symptoms associated with such diseases or conditions.
Public/Granted literature
- US20120283309A1 SIRNA COMPOUNDS COMPRISING TERMINAL SUBSTITUTIONS Public/Granted day:2012-11-08
Information query
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