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US08796241B2 Therapy of tumors and infectious agents deficient in methylthioadenosine phosphorylase 有权
治疗甲基硫代腺苷磷酸化酶缺乏的肿瘤和感染因子

Therapy of tumors and infectious agents deficient in methylthioadenosine phosphorylase
Abstract:
Methods for treating diseases in humans and vertebrate animals are provided using competitive antagonists of cellular metabolites combined with a protective agent for protecting host cells from toxic effects of the drugs. Also provided are kits comprising competitive antagonists and suitable protective agents. In addition, screening methods for identifying competitive antagonists, protective agents and potentiating agents, for use according to the methods of the invention, are provided.
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