Invention Grant
US08796265B2 Anti-infective solution comprising a compound of pyrido(3,2,1-IJ)-benzoxadiazine type
有权
包含吡啶并(3,2,1-I) - 苯并恶嗪类化合物的抗感染溶液
- Patent Title: Anti-infective solution comprising a compound of pyrido(3,2,1-IJ)-benzoxadiazine type
- Patent Title (中): 包含吡啶并(3,2,1-I) - 苯并恶嗪类化合物的抗感染溶液
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Application No.: US12161827Application Date: 2007-01-24
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Publication No.: US08796265B2Publication Date: 2014-08-05
- Inventor: Marinette Moreau
- Applicant: Marinette Moreau
- Applicant Address: FR
- Assignee: SA Vetoquinol
- Current Assignee: SA Vetoquinol
- Current Assignee Address: FR
- Agency: DLA Piper LLP (US)
- Priority: FR0650246 20060124
- International Application: PCT/FR2007/050682 WO 20070124
- International Announcement: WO2007/085760 WO 20070802
- Main IPC: A61K31/5395
- IPC: A61K31/5395 ; A61P31/00 ; A61K9/00

Abstract:
An anti-infection solution including (i) from 10% to 30% by weight with respect to the total volume of the solution of at least one compound of Formula (I): wherein: X represents a hydrogen or halogen atom or a hydroxy function, R1 represents: a 1-piperazinyl radical, which may be substituted in position 4 by a methyl, acetyl or 4-aminobenzyl group; a morpholino radical: a 1-pyrrolidinyl radical substituted in position 3 by a chlorine atom or by an amino, aminomethyl, (methylamino) methyl, (ethylamino) methyl or methoxy group; a 1-imidazolyl radical that can be substituted in position 4 by the methyl group, or a 1-piperidyl radical substituted in position 4 by a hydroxy or methoxy group, and R2 represents an alkyl radical, linear, branched or ring, including 1 to 10 carbon atoms, or at least one of its pharmaceutically acceptable salts, (ii) benzyl alcohol as a stabilizing agent, and at least one stabilizing agent, and (iii) at least one solubilization agent selected from the group consisting of carbolic acids and their esters, in a pharmaceutically acceptable carrier.
Public/Granted literature
- US20100280022A1 ANTI-INFECTIVE SOLUTION COMPRISING A COMPOUND OF PYRIDO(3,2,1-IJ)-BENZOXADIAZINE TYPE Public/Granted day:2010-11-04
Information query
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