Invention Grant
- Patent Title: 2,3-disubstituted pyrazinesulfonamides as CRTH2 inhibitors
- Patent Title (中): 2,3-二取代吡嗪磺酰胺作为CRTH2抑制剂
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Application No.: US11918294Application Date: 2006-04-20
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Publication No.: US08796280B2Publication Date: 2014-08-05
- Inventor: Patrick Page , Matthias Schwarz , Eric Sebille , Christophe Cleva , Cedric Merlot , Maurizio Maio
- Applicant: Patrick Page , Matthias Schwarz , Eric Sebille , Christophe Cleva , Cedric Merlot , Maurizio Maio
- Applicant Address: CH Coinsins, Vaud
- Assignee: Merck Serono, S.A.
- Current Assignee: Merck Serono, S.A.
- Current Assignee Address: CH Coinsins, Vaud
- Agency: EMD Serono Research and Development Institute
- Agent Thomas W. Brown
- Priority: EP05103254 20050421
- International Application: PCT/EP2006/061706 WO 20060420
- International Announcement: WO2006/111560 WO 20061026
- Main IPC: A61K31/4965
- IPC: A61K31/4965 ; C07D409/12 ; C07D401/10 ; C07D241/22 ; C07D413/10 ; C07D405/12 ; C07D403/10 ; C07D401/12
Abstract:
The present invention is related to the use of 2,3 substituted pyrazine sulfonamides of formula (I) for the treatment and/or prevention of allergic diseases, inflammatory dermatoses and other diseases with an inflammatory component. Specifically, the present invention is related to the use of 2,3 substituted pyrazine sulfonamides for the modulation, notably the inhibition, of CRTH2 activity.
Public/Granted literature
- US20090054447A1 2,3 Substituted Pyrazine Sulfonamides as Inhibitors of CRTH2 Public/Granted day:2009-02-26
Information query
