Invention Grant
US08796310B2 Amino-pyridine-containing spleen tyrosine kinase (SYK) inhibitors
有权
含氨基吡啶的脾脏酪氨酸激酶(SYK)抑制剂
- Patent Title: Amino-pyridine-containing spleen tyrosine kinase (SYK) inhibitors
- Patent Title (中): 含氨基吡啶的脾脏酪氨酸激酶(SYK)抑制剂
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Application No.: US13704484Application Date: 2012-04-30
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Publication No.: US08796310B2Publication Date: 2014-08-05
- Inventor: Eric Thomas Romeo , Michelle R. Machacek , Benjamin Wesley Trotter , Thomas Allen Miller , Brian Michael Andresen , Neville John Anthony , Brandon M. Taoka , Yuan Liu
- Applicant: Eric Thomas Romeo , Michelle R. Machacek , Benjamin Wesley Trotter , Thomas Allen Miller , Brian Michael Andresen , Neville John Anthony , Brandon M. Taoka , Yuan Liu
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Eric A. Meade; Valerie J. Camara
- International Application: PCT/US2012/035725 WO 20120430
- International Announcement: WO2012/151137 WO 20121108
- Main IPC: A61K31/444
- IPC: A61K31/444 ; C07D277/04

Abstract:
The invention provides certain amino-pyridine-containing compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and n are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.
Public/Granted literature
- US20130090309A1 AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS Public/Granted day:2013-04-11
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