Invention Grant
- Patent Title: Heteroaryl derivatives as CFTR modulators
- Patent Title (中): 杂芳基衍生物作为CFTR调节剂
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Application No.: US13627222Application Date: 2012-09-26
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Publication No.: US08796312B2Publication Date: 2014-08-05
- Inventor: Sara Hadida Ruah , Mark Miller , Jinglan Zhou , Brian Bear
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agent Susan C. Kelly
- Main IPC: C07D213/75
- IPC: C07D213/75 ; A61K31/435
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Public/Granted literature
- US20130023538A1 Heteroaryl Derivatives as CFTR Modulators Public/Granted day:2013-01-24
Information query
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