A gamma correction system and method for a display device are disclosed. According to one aspect, the gamma correction system includes a display panel configured to display an image, a measuring unit configured to acquire optical characteristic information from the image displayed on the display panel, and a display panel driver configured to convert a gamma data result value obtained after performing optical compensation for at least two sample gray values among a plurality of reference luminance values into a corresponding data voltage and calculate a data voltage for the rest of the luminance values for which optical compensation is not performed.