A system and corresponding method for selectively communicating data between a first device and a second device is provided. An indication of a configuration of the second device is received by the first device. A selection signal is generated based on the configuration. Universal Serial Bus (USB) protocol data, uncompressed high definition media data, or a combination thereof may be caused to be selectively supplied to the second device by the first device based on the selection signal. The first device may be configured to transmit, on a DisplayPort link to the second device, a data flow comprising both USB protocol data and uncompressed high definition media data signals. The devices may be configured such that the USB protocol data is transferred from the second device to the first device during a video blanking period associated with the uncompressed high definition media data signals.