Invention Grant
- Patent Title: Compositions and methods for diagnosing and treating cancer
- Patent Title (中): 用于诊断和治疗癌症的组合物和方法
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Application No.: US12121348Application Date: 2008-05-15
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Publication No.: US08802103B2Publication Date: 2014-08-12
- Inventor: Austin Gurney , Timothy Hoey , Sanjeev Satyal , Maureen Fitch Bruhns
- Applicant: Austin Gurney , Timothy Hoey , Sanjeev Satyal , Maureen Fitch Bruhns
- Applicant Address: US CA Redwood City
- Assignee: OncoMed Pharmaceuticals, Inc.
- Current Assignee: OncoMed Pharmaceuticals, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/18 ; C07K16/22 ; C07K16/32
Abstract:
Monoclonal antibodies that specifically bind to an extracellular domain of human Jagged 1 and inhibit growth of a tumor comprising cancer stem cells are described. Also described is a method of treating cancer that comprises administering a therapeutically effective amount of a monoclonal anti-Jagged 1 antibody.
Public/Granted literature
- US20080317760A1 Compositions and Methods for Diagnosing and Treating Cancer Public/Granted day:2008-12-25
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