Invention Grant
- Patent Title: Peptide compositions and methods for inhibiting herpesvirus infection
- Patent Title (中): 肽组合物和抑制疱疹病毒感染的方法
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Application No.: US13505099Application Date: 2010-10-29
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Publication No.: US08802106B2Publication Date: 2014-08-12
- Inventor: Lilia I. Melnik , Robert F. Garry , Cindy A. Morris
- Applicant: Lilia I. Melnik , Robert F. Garry , Cindy A. Morris
- Applicant Address: US LA New Orleans
- Assignee: The Administrators of the Tulane Educational Fund
- Current Assignee: The Administrators of the Tulane Educational Fund
- Current Assignee Address: US LA New Orleans
- Agency: Olson & Cepuritis, Ltd.
- International Application: PCT/US2010/054743 WO 20101029
- International Announcement: WO2011/053798 WO 20110505
- Main IPC: C07K14/045
- IPC: C07K14/045 ; A61P31/22 ; A61K39/245 ; C07K14/005 ; A61K39/00 ; A61K38/00
Abstract:
The present invention provides an isolated peptide having an amino acid residue sequence that comprises at least one human cytomegalovirus glycoprotein B (HCMV-gB) sequence segment, each HCMV-gB sequence segment consisting of at least 8 and not more than 60 consecutive amino acid residues from residues 146 to 315, residues 476 to 494 of SEQ ID NO: 1, or from a sequence variant of residues 146 to 315 or 476 to 494 of SEQ ID NO: 1 that has at least 70% sequence identity thereto. The peptides of the invention are useful for treating, preventing, or inhibiting a herpesvirus (e.g., Herpes Simplex Virus-1, Human Cytomegalovirus, and the like) infection in a subject.
Public/Granted literature
- US20130005648A1 PEPTIDE COMPOSITIONS AND METHODS FOR INHIBITING HERPESVIRUS INFECTION Public/Granted day:2013-01-03
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