Invention Grant
US08802111B2 Manufacture of vaccines that contain both hepatitis B virus surface antigens and surfactant
有权
制造含有乙型肝炎病毒表面抗原和表面活性剂的疫苗
- Patent Title: Manufacture of vaccines that contain both hepatitis B virus surface antigens and surfactant
- Patent Title (中): 制造含有乙型肝炎病毒表面抗原和表面活性剂的疫苗
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Application No.: US13302279Application Date: 2011-11-22
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Publication No.: US08802111B2Publication Date: 2014-08-12
- Inventor: Mario Contorni
- Applicant: Mario Contorni
- Applicant Address: IT Siena
- Assignee: Novartis Vaccines and Diagnostics, SRL
- Current Assignee: Novartis Vaccines and Diagnostics, SRL
- Current Assignee Address: IT Siena
- Agency: Robins Law Group
- Agent Roberta L. Robins
- Priority: GB0522765.7 20051108
- Main IPC: A61K39/29
- IPC: A61K39/29 ; C07K14/005 ; A61K39/12 ; C07K1/26 ; A61K39/00
Abstract:
When preparing HBsAg for use in a combination vaccine, it us known to add a non-ionic detergent after the HBsAg has been purified. Adding detergents after purification of HBsAg is not optimal, however, as it requires a separate processing step during manufacture. Thus the invention uses them during HBsAg purification.
Public/Granted literature
- US20120107345A1 MANUFACTURE OF VACCINES THAT CONTAIN BOTH HEPATITIS B VIRUS SURFACE ANTIGENS AND SURFACTANT Public/Granted day:2012-05-03
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