Invention Grant
- Patent Title: Multi-phased, biodegradable and osteointegrative composite scaffold for biological fixation of musculoskeletal soft tissue of bone
- Patent Title (中): 多相,可生物降解和骨整合复合支架用于骨骼肌骨骼软组织的生物固定
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Application No.: US12655193Application Date: 2009-12-22
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Publication No.: US08802122B2Publication Date: 2014-08-12
- Inventor: Helen H. Lu , Jeffrey Spalazzi , Kathie Dionisio
- Applicant: Helen H. Lu , Jeffrey Spalazzi , Kathie Dionisio
- Applicant Address: US NY New York
- Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee Address: US NY New York
- Agency: Cooper & Dunham LLP
- Agent John P. White
- Main IPC: A61F2/02
- IPC: A61F2/02

Abstract:
Methods and apparatuses are provided for musculoskeletal tissue engineering. For example, a scaffold apparatus is provided which comprises microspheres of selected sizes and/or composition. The microspheres are layered to have a gradient of microsphere sizes and/or compositions. The scaffold provides a functional interface between multiple tissue types.
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