Invention Grant
- Patent Title: Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
- Patent Title (中): 含质子泵抑制剂的胶囊包含不同结构的用于活性成分的延迟释放的亚基
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Application No.: US10561700Application Date: 2004-06-03
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Publication No.: US08802139B2Publication Date: 2014-08-12
- Inventor: Isa Odidi , Amina Odidi
- Applicant: Isa Odidi , Amina Odidi
- Applicant Address: CA Ontario
- Assignee: Intellipharmaceutics Corp.
- Current Assignee: Intellipharmaceutics Corp.
- Current Assignee Address: CA Ontario
- Agency: Thomas Horstemeyer, LLP
- International Application: PCT/CA2004/000825 WO 20040603
- International Announcement: WO2004/112756 WO 20041229
- Main IPC: A61K9/48
- IPC: A61K9/48 ; A61K9/52 ; A61K31/4439
Abstract:
An oral pharmaceutical composition comprises multiple populations of at least one of beads, pellets, tablets and granules provided in a capsule, the composition comprising: a first population of a pharmaceutical active comprising a pharmaceutical active substance releasable at a first rate; a population of a basic substance; and a second population of a pharmaceutical active comprising a pharmaceutical active substance releasable at a second rate. In another embodiment, the oral pharmaceutical composition comprises multiple populations of at least one of beads, pellets, tablets and granules provided in a capsule, the composition comprising: a population of a pharmaceutical active; a population of a basic substance; a population of enteric coated pharmaceutical active; and a population of enteric coated basic substance. The composition can provide multiple site specific delivery of a pharmaceutical active in a rapid, delayed and/or sustained release manner into the plasma.
Public/Granted literature
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