Invention Grant
- Patent Title: 4-hydroxybenzomorphans
- Patent Title (中): 4-羟基苯并吗啡
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Application No.: US14169305Application Date: 2014-01-31
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Publication No.: US08802655B2Publication Date: 2014-08-12
- Inventor: Mark P. Wentland
- Applicant: Rensselaer Polytechnic Institute
- Applicant Address: US NY Troy
- Assignee: Rensselaer Polytechnic Institute
- Current Assignee: Rensselaer Polytechnic Institute
- Current Assignee Address: US NY Troy
- Agency: Heslin Rothenberg Farley & Mesiti P.C.
- Main IPC: A61K31/4748
- IPC: A61K31/4748 ; C07D221/26

Abstract:
4-Hydroxybenzomorphans containing carboxamide or thiocarboxamide at the 3-position are useful as analgesics, anti-diarrheal agents, anticonvulsants, antitussives and anti-addiction medications. A compound of formula is disclosed, as are pharmaceutically acceptable acid addition salts, such as acetic, benzenesulfonic (besylate), benzoic, camphorsulfonic, citric, ethenesulfonic, fumaric, gluconic, glutamic, hydrobromic, hydrochloric, isethionic, lactic, maleic, malic, mandelic, methanesulfonic, mucic, nitric, pamoic, pantothenic, phosphoric, succinic, sulfuric, tartaric acid or p-toluenesulfonic acid salts. These compounds are useful for the treatment of pain.
Public/Granted literature
- US20140148475A1 4-HYDROXYBENZOMORPHANS Public/Granted day:2014-05-29
Information query
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