Invention Grant
US08802661B2 C-28 amides of modified C-3 betulinic acid derivatives as HIV maturation inhibitors
有权
改性C-3桦木酸衍生物的C-28酰胺作为HIV成熟抑制剂
- Patent Title: C-28 amides of modified C-3 betulinic acid derivatives as HIV maturation inhibitors
- Patent Title (中): 改性C-3桦木酸衍生物的C-28酰胺作为HIV成熟抑制剂
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Application No.: US13151722Application Date: 2011-06-02
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Publication No.: US08802661B2Publication Date: 2014-08-12
- Inventor: Alicia Regueiro-Ren , Zheng Liu , Jacob Swidorski , Nicholas A. Meanwell , Sing-Yuen Sit , Jie Chen , Yan Chen , Ny Sin
- Applicant: Alicia Regueiro-Ren , Zheng Liu , Jacob Swidorski , Nicholas A. Meanwell , Sing-Yuen Sit , Jie Chen , Yan Chen , Ny Sin
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent John F. Levis
- Main IPC: A61K31/56
- IPC: A61K31/56 ; A61K31/58 ; C07J53/00
Abstract:
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, modified C-3 and C-28 betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors. These compounds are useful for the treatment of HIV and AIDS.
Public/Granted literature
- US20120142653A1 C-28 AMIDES OF MODIFIED C-3 BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS Public/Granted day:2012-06-07
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