Invention Grant
- Patent Title: Aminopyrimidine derivatives as LRRK2 modulators
- Patent Title (中): 氨基嘧啶衍生物作为LRRK2调节剂
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Application No.: US13712015Application Date: 2012-12-12
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Publication No.: US08802674B2Publication Date: 2014-08-12
- Inventor: Charles Baker-Glenn , Daniel Jon Burdick , Mark Chambers , Bryan K. Chan , Huifen Chen , Anthony Estrada , Janet Gunzner-Tate , Daniel Shore , Zachary Kevin Sweeney , Shumei Wang , Guiling Zhao
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Robert C. Hall
- Main IPC: A61K31/535
- IPC: A61K31/535 ; C07D413/14 ; C07D498/06 ; C07D473/16 ; C07D403/14 ; C07D413/12
Abstract:
Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n. X, R1, R2, R3, R5, R6 and R7 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with LRRK2 receptor, such as Parkinson's disease.
Public/Granted literature
- US20130096102A1 AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS Public/Granted day:2013-04-18
Information query
