Invention Grant
- Patent Title: Arylamino N-heteraryl compounds as MEK inhibitors
- Patent Title (中): 芳基氨基N-杂芳基化合物作为MEK抑制剂
-
Application No.: US12815071Application Date: 2010-06-14
-
Publication No.: US08802703B2Publication Date: 2014-08-12
- Inventor: Andreas Goutopoulos , Benny C. Askew, Jr. , Nhut Kiet Diep , Srinivasa R. Karra , Matthias Schwarz , Henry Yu
- Applicant: Andreas Goutopoulos , Benny C. Askew, Jr. , Nhut Kiet Diep , Srinivasa R. Karra , Matthias Schwarz , Henry Yu
- Applicant Address: CH Coinsins, Vaud
- Assignee: Merck Serono S.A.
- Current Assignee: Merck Serono S.A.
- Current Assignee Address: CH Coinsins, Vaud
- Agency: EMD Serono Research & Development Institute
- Agent Thomas W. Brown
- Main IPC: A61K31/465
- IPC: A61K31/465 ; A61K31/4412 ; A61K31/44 ; C07D213/81 ; C07D213/80 ; C07D213/82 ; C07D405/12 ; C07D213/84 ; C07D237/24 ; C07D213/79 ; A61P35/00 ; A61P29/00
Abstract:
The invention provides novel arylamino N-heteroaryl MEK inhibitors of Formula (I): Such compounds are MEK inhibitors that are useful in the treatment of hyperproliferative diseases, such as cancer and inflammation. Also disclosed is the treatment of a hyperproliferative disease in mammals, and pharmaceutical compositions containing such compounds.
Public/Granted literature
- US20100256149A1 NOVEL ARYLAMINO N-HETERARYL COMPOUNDS AS MEK INHIBITORS Public/Granted day:2010-10-07
Information query
