A resistor-2 resistor (R-2R) digital-to-analog converter with partial resistor network reconfiguration. A circuit includes a plurality of resistor stacks. The circuit also includes a plurality of separation resistors which separate each of the plurality of resistor stacks. The circuit further includes a first selection circuit connected to a first resistor stack of the plurality of resistor stacks and a plurality of selection circuits connected between the plurality of separation resistors. The circuit also includes a termination resistor stack connected to a drain of the first resistor stack.