Invention Grant
US08808683B2 Genetically modified bacterium of the species Listeria monocytogenes
有权
单核细胞增生李斯特菌属的转基因细菌
- Patent Title: Genetically modified bacterium of the species Listeria monocytogenes
- Patent Title (中): 单核细胞增生李斯特菌属的转基因细菌
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Application No.: US13701142Application Date: 2011-04-29
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Publication No.: US08808683B2Publication Date: 2014-08-19
- Inventor: Peter Rossmanith , Karin Fruehwirth , Martin Wagner , Sabine Fuchs
- Applicant: Peter Rossmanith , Karin Fruehwirth , Martin Wagner , Sabine Fuchs
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: EP10005731 20100602
- International Application: PCT/EP2011/002147 WO 20110429
- International Announcement: WO2011/150999 WO 20111208
- Main IPC: A61K39/02
- IPC: A61K39/02 ; A01N63/00 ; C07H21/02
Abstract:
The present invention relates to a genetically modified bacterium of the species Listeria monocytogenes, wherein the genomic locus of the transcriptional factor PrfA has been deleted, characterized in that it comprises on genomic level an artificial sequence that acts as internal amplification control, the use of this bacterium as well as a method for detecting and determining qualitatively and/or quantitatively the occurrence of wild type Listeria monocytogenes in a sample suspected to be contaminated with said micro-organism and a kit.
Public/Granted literature
- US20130137100A1 GENETICALLY MODIFIED BACTERIUM OF THE SPECIES LISTERIA MONOCYTOGENES Public/Granted day:2013-05-30
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