Invention Grant
- Patent Title: Helper virus-free AAV production
- Patent Title (中): 帮助无病毒的AAV生产
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Application No.: US12140820Application Date: 2008-06-17
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Publication No.: US08809058B2Publication Date: 2014-08-19
- Inventor: Forrest K. Ferrari , Xiao Xiao , Richard Jude Samulski
- Applicant: Forrest K. Ferrari , Xiao Xiao , Richard Jude Samulski
- Applicant Address: US NC Chapel Hill
- Assignee: The University of North Carolina at Chapel Hill
- Current Assignee: The University of North Carolina at Chapel Hill
- Current Assignee Address: US NC Chapel Hill
- Agency: Jenkins, Wilson, Taylor & Hunt, P.A.
- Main IPC: C12N15/63
- IPC: C12N15/63 ; C12N15/64 ; C12N15/861 ; C12N15/86 ; C12N15/864 ; A61K48/00
Abstract:
A method for the production of adeno-associated virus stocks and recombinant adeno-associated virus stocks that are substantially free of contaminating helper virus is described. The method utilizes transfection with helper virus vectors to replace the infection with helper virus used in the conventional method.
Public/Granted literature
- US20090004743A1 HELPER VIRUS-FREE AAV PRODUCTION Public/Granted day:2009-01-01
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