Invention Grant
US08809279B2 Peptides that are modulators of the protein TRF2 and compositions containing same
有权
作为蛋白质TRF2的调节剂的肽和含有它们的组合物
- Patent Title: Peptides that are modulators of the protein TRF2 and compositions containing same
- Patent Title (中): 作为蛋白质TRF2的调节剂的肽和含有它们的组合物
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Application No.: US14114965Application Date: 2012-04-27
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Publication No.: US08809279B2Publication Date: 2014-08-19
- Inventor: Claude Dal Farra , Nouha Domloge , Jean-Marie Botto
- Applicant: Claude Dal Farra , Nouha Domloge , Jean-Marie Botto
- Applicant Address: US DE Wilmington
- Assignee: ISP Investments Inc.
- Current Assignee: ISP Investments Inc.
- Current Assignee Address: US DE Wilmington
- Agency: Thompson Hine L.L.P.
- Priority: FR1101348 20110502
- International Application: PCT/FR2012/000166 WO 20120427
- International Announcement: WO2012/153015 WO 20121115
- Main IPC: A61K38/09
- IPC: A61K38/09 ; A61K38/10 ; A61K8/64 ; C07K7/06 ; C07K7/08 ; A61Q19/00 ; A61Q19/08 ; A61K38/08 ; C07K14/47
Abstract:
Peptide compounds of the following general formula (I): R1-(AA)n-X1-X2-X3-Lys-Lys-Gln-Lys-Trp-X4-(AA)p-R2 are disclosed herein. The peptide compounds can be used as Telomeric repeat-binding factor 2 (TRF2) protein-modulating compounds and have a preventive action on deoxyribonucleic acid (DNA) double-strand breaks. In addition, cosmetic compositions that include at least one peptide of general formula (I) in a physiologically acceptable medium are disclosed along with methods for preventing and/or treating cutaneous signs of aging and photoaging.
Public/Granted literature
- US20140066381A1 NOVEL PEPTIDES THAT ARE MODULATORS OF THE PROTEIN TRF2 AND COMPOSITIONS CONTAINING SAME Public/Granted day:2014-03-06
Information query
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