Invention Grant
US08809281B2 Small peptides and methods for blocking IGE mediated activation of an immune cell
有权
小肽和阻断IGE介导的免疫细胞活化的方法
- Patent Title: Small peptides and methods for blocking IGE mediated activation of an immune cell
- Patent Title (中): 小肽和阻断IGE介导的免疫细胞活化的方法
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Application No.: US13908721Application Date: 2013-06-03
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Publication No.: US08809281B2Publication Date: 2014-08-19
- Inventor: John C. Houck , James Clagett
- Applicant: Mowycal Lending, LLC
- Applicant Address: US AZ Phoenix
- Assignee: Mowycal Lending, LLC
- Current Assignee: Mowycal Lending, LLC
- Current Assignee Address: US AZ Phoenix
- Agency: Lathrop & Gage LLP
- Agent Dan Cleveland, Jr.
- Main IPC: A61K38/07
- IPC: A61K38/07 ; A61K38/00

Abstract:
Methods for treating cutaneous inflammation, are described. Also described is a method for inhibiting the mucous release into airways of a patient, a method for blocking IgE activation of an immune cell, a method for stabilizing the cell membrane of an immune cell, thereby preventing their further involvement in the increased inflammatory response to an IgE antigen challenge, and a method for inhibiting the migration of T-cells. Such methods involve administering to said patient a therapeutically effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.
Public/Granted literature
- US20130252907A1 Small Peptides And Methods For Blocking IgE Mediated Activation Of An Immune Cell Public/Granted day:2013-09-26
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