Invention Grant
- Patent Title: Apoptosis inducer for cancer cell
- Patent Title (中): 癌细胞凋亡诱导剂
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Application No.: US13629226Application Date: 2012-09-27
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Publication No.: US08809296B2Publication Date: 2014-08-19
- Inventor: Motoki Takagi , Akira Shimamoto , Yasuhiro Furuichi , Ayumi Sato
- Applicant: Genecare Research Institute Co., Ltd.
- Applicant Address: JP Kamakura-shi
- Assignee: Genecare Research Institute Co., Ltd.
- Current Assignee: Genecare Research Institute Co., Ltd.
- Current Assignee Address: JP Kamakura-shi
- Agency: Seed IP Law Group PLLC
- Priority: JP2003-140685 20030519
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C07H21/02

Abstract:
The present invention revealed that by suppressing the expression of the WRN gene, the BLM gene, or the RecQ1 gene, which belong to the RecQ helicase family, apoptosis is induced in various cancer cells and their proliferation is suppressed. Compounds that suppress the expression of RecQ helicase family genes or the functions of RecQ helicase proteins are thought to have the activity of inducing apoptosis.
Public/Granted literature
- US20130090370A1 APOPTOSIS INDUCER FOR CANCER CELL Public/Granted day:2013-04-11
Information query
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