Invention Grant
US08809303B2 Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation
有权
调节肌动蛋白细胞骨架重排和细胞间隙形成的方法
- Patent Title: Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation
- Patent Title (中): 调节肌动蛋白细胞骨架重排和细胞间隙形成的方法
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Application No.: US12936801Application Date: 2009-04-09
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Publication No.: US08809303B2Publication Date: 2014-08-19
- Inventor: Thomas Michael Egan
- Applicant: Thomas Michael Egan
- Applicant Address: US NC Chapel Hill
- Assignee: The University of North Carolina at Chapel Hill
- Current Assignee: The University of North Carolina at Chapel Hill
- Current Assignee Address: US NC Chapel Hill
- Agency: Jenkins, Wilson, Taylor & Hunt, P.A.
- International Application: PCT/US2009/040098 WO 20090409
- International Announcement: WO2009/126822 WO 20091015
- Main IPC: A61K31/70
- IPC: A61K31/70
Abstract:
Methods are described for reducing cytoskeletal rearrangement and intercellular gap formation by contacting cells with an aminoalkyl glucosaminide phosphate. In particular, the methods can be used to reduce actin cytoskeletal rearrangement and/or intracellular gap formation related to ischemic or ischemia-reperfusion events and to alleviate diseases or conditions related to increased actin cytoskeletal rearrangement.
Public/Granted literature
- US20110053871A1 METHODS OF REGULATING ACTIN CYTOSKELETAL REARRANGEMENT AND INTERCELLULAR GAP FORMATION Public/Granted day:2011-03-03
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