Invention Grant
US08809337B2 Carbamoyl derivatives of bicyclic carbonylamino-pyrazoles as prodrugs
有权
双环羰基氨基 - 吡唑的氨基甲酰衍生物作为前药
- Patent Title: Carbamoyl derivatives of bicyclic carbonylamino-pyrazoles as prodrugs
- Patent Title (中): 双环羰基氨基 - 吡唑的氨基甲酰衍生物作为前药
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Application No.: US13630009Application Date: 2012-09-28
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Publication No.: US08809337B2Publication Date: 2014-08-19
- Inventor: Maurizio Pulici , Paolo Polucci
- Applicant: Nerviano Medical Sciences S.R.L.
- Applicant Address: IT Nerviano (MI)
- Assignee: Nerviano Medical Sciences S.R.L.
- Current Assignee: Nerviano Medical Sciences S.R.L.
- Current Assignee Address: IT Nerviano (MI)
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: EP08156262 20080515
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K31/4162 ; A61K31/454 ; C07D401/14 ; C07D401/12 ; C07D495/04
Abstract:
There are provided bicyclic carbonylamino-pyrazoles of formula (I), wherein the variables are as specified in the claims, for use as medicament, in particular for the treatment of diseases due to the malfunctioning of protein kinases (PKs), such as cancer, pharmaceutical compositions comprising such carbamoyl derivatives, and their use as prodrugs of therapeutically active agents. Method of treatment and some new bicyclic carbonylamino-pyrazoles are also object of the present invention.
Public/Granted literature
- US20130203770A1 CARBAMOYL DERIVATIVES OF BICYCLIC CARBONYLAMINO-PYRAZOLES AS PRODRUGS Public/Granted day:2013-08-08
Information query
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