Invention Grant
US08809338B2 1,2,3-triazole-based peptidomimetic integrin inhibitors for the diagnosis and therapy of tumors
有权
用于诊断和治疗肿瘤的1,2,3-三唑类拟肽整联蛋白抑制剂
- Patent Title: 1,2,3-triazole-based peptidomimetic integrin inhibitors for the diagnosis and therapy of tumors
- Patent Title (中): 用于诊断和治疗肿瘤的1,2,3-三唑类拟肽整联蛋白抑制剂
-
Application No.: US13578246Application Date: 2011-02-14
-
Publication No.: US08809338B2Publication Date: 2014-08-19
- Inventor: Antonio Guarna , Gloria Menchi , Nicoletta Cini , Andrea Trabocchi , Alberto Pupi , Anna Bottoncetti , Silvia Raspanti , Lido Calorini
- Applicant: Antonio Guarna , Gloria Menchi , Nicoletta Cini , Andrea Trabocchi , Alberto Pupi , Anna Bottoncetti , Silvia Raspanti , Lido Calorini
- Applicant Address: IT Florence
- Assignee: Universita' Degli Studi di Firenze
- Current Assignee: Universita' Degli Studi di Firenze
- Current Assignee Address: IT Florence
- Agency: DLA Piper LLP (US)
- Priority: ITFI2010A0019 20100212
- International Application: PCT/EP2011/052139 WO 20110214
- International Announcement: WO2011/098603 WO 20110818
- Main IPC: A61K31/497
- IPC: A61K31/497 ; A61K31/41 ; A61K31/415
Abstract:
The present invention refers to the field of chemical compounds bearing a 1,2,3-triazole ring of formula (I) and possessing guanidino and carboxylic groups or their isosteres, their preparation by Cu-catalyzed “click-chemistry”, and medical-diagnostic use in pathologies where angiogenesis is altered, for example pathologic conditions of tumor origin, tumor metastasis, osteoporosis, and rheumatoid arthritis.
Public/Granted literature
- US20130040964A1 1,2,3-TRIAZOLE-BASED PEPTIDOMIMETIC INTEGRIN INHIBITORS FOR THE DIAGNOSIS AND THERAPY OF TUMORS Public/Granted day:2013-02-14
Information query
IPC分类:
