Invention Grant
- Patent Title: Glucagon receptor modulators
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Application No.: US13334202Application Date: 2011-12-22
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Publication No.: US08809342B2Publication Date: 2014-08-19
- Inventor: Gary Erik Aspnes , Mary Theresa Didiuk , Kevin James Filipski , Angel Guzman-Perez , Jeffrey Allen Pfefferkorn , Benjamin Dawson Stevens , Meihua Mike Tu
- Applicant: Gary Erik Aspnes , Mary Theresa Didiuk , Kevin James Filipski , Angel Guzman-Perez , Jeffrey Allen Pfefferkorn , Benjamin Dawson Stevens , Meihua Mike Tu
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent James T. Wasicak
- Main IPC: C07D401/12
- IPC: C07D401/12 ; A61K31/4427

Abstract:
The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.
Public/Granted literature
- US20120165343A1 Glucagon Receptor Modulators Public/Granted day:2012-06-28
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