Invention Grant
US08809352B2 Sulfonamides as inhibitors of Bcl-2 family proteins for the treatments of cancer
有权
磺酰胺作为Bcl-2家族蛋白的抑制剂用于治疗癌症
- Patent Title: Sulfonamides as inhibitors of Bcl-2 family proteins for the treatments of cancer
- Patent Title (中): 磺酰胺作为Bcl-2家族蛋白的抑制剂用于治疗癌症
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Application No.: US13394525Application Date: 2010-09-08
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Publication No.: US08809352B2Publication Date: 2014-08-19
- Inventor: Karen Miller-Moslin , Bakary-Barry Toure , Michael Scott Visser , Naeem Yusuff
- Applicant: Karen Miller-Moslin , Bakary-Barry Toure , Michael Scott Visser , Naeem Yusuff
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Scott W. Reid
- International Application: PCT/EP2010/063169 WO 20100908
- International Announcement: WO2011/029842 WO 20110317
- Main IPC: A01N43/62
- IPC: A01N43/62 ; A61K31/55 ; A61K31/497 ; A01N43/90 ; A61K31/519 ; A01N43/64 ; A61K31/41 ; C07D471/00 ; C07D487/00 ; C07D471/04
Abstract:
The present invention includes novel compound and methods of treating a disease or disorder by antagonizing Bcl-2 family proteins, particularly compounds of formula (I): or pharmaceutically acceptable salt thereof, as well as methods of treating a disease, disorder, or syndrome associated with Bcl-2 inhibition, particularly hyperproliferative diseases. The present invention also includes pharmaceutical compositions including compounds of formula I and pharmaceutically acceptable salts thereof.
Public/Granted literature
- US20120165298A1 SULFONAMIDE COMPOUNDS Public/Granted day:2012-06-28
Information query
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