Invention Grant
US08809361B2 2,3-dihydrofuro[2,3-c]pyridines, their use as modulators of the G-protein-coupled receptor GPR119 and pharmaceutical compositions thereof
有权
2,3-二氢呋喃并[2,3-c]吡啶,它们用作G蛋白偶联受体GPR119的调节剂及其药物组合物
- Patent Title: 2,3-dihydrofuro[2,3-c]pyridines, their use as modulators of the G-protein-coupled receptor GPR119 and pharmaceutical compositions thereof
- Patent Title (中): 2,3-二氢呋喃并[2,3-c]吡啶,它们用作G蛋白偶联受体GPR119的调节剂及其药物组合物
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Application No.: US13887887Application Date: 2013-05-06
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Publication No.: US08809361B2Publication Date: 2014-08-19
- Inventor: Matthias Eckhardt
- Applicant: Matthias Eckhardt
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Timothy X. Witkowski
- Priority: EP12166992 20120507
- Main IPC: C07D491/20
- IPC: C07D491/20 ; A61K31/438
![2,3-dihydrofuro[2,3-c]pyridines, their use as modulators of the G-protein-coupled receptor GPR119 and pharmaceutical compositions thereof](/abs-image/US/2014/08/19/US08809361B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to compounds of general formula I, wherein the groups R1 and A are as defined in the application, which have valuable pharmacological properties, and in particular bind to the GPR119 receptor and modulate its activity.
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