Invention Grant
US08809361B2 2,3-dihydrofuro[2,3-c]pyridines, their use as modulators of the G-protein-coupled receptor GPR119 and pharmaceutical compositions thereof 有权
2,3-二氢呋喃并[2,3-c]吡啶,它们用作G蛋白偶联受体GPR119的调节剂及其药物组合物

  • Patent Title: 2,3-dihydrofuro[2,3-c]pyridines, their use as modulators of the G-protein-coupled receptor GPR119 and pharmaceutical compositions thereof
  • Patent Title (中): 2,3-二氢呋喃并[2,3-c]吡啶,它们用作G蛋白偶联受体GPR119的调节剂及其药物组合物
  • Application No.: US13887887
    Application Date: 2013-05-06
  • Publication No.: US08809361B2
    Publication Date: 2014-08-19
  • Inventor: Matthias Eckhardt
  • Applicant: Matthias Eckhardt
  • Applicant Address: DE Ingelheim am Rhein
  • Assignee: Boehringer Ingelheim International GmbH
  • Current Assignee: Boehringer Ingelheim International GmbH
  • Current Assignee Address: DE Ingelheim am Rhein
  • Agent Michael P. Morris; Timothy X. Witkowski
  • Priority: EP12166992 20120507
  • Main IPC: C07D491/20
  • IPC: C07D491/20 A61K31/438
2,3-dihydrofuro[2,3-c]pyridines, their use as modulators of the G-protein-coupled receptor GPR119 and pharmaceutical compositions thereof
Abstract:
The present invention relates to compounds of general formula I, wherein the groups R1 and A are as defined in the application, which have valuable pharmacological properties, and in particular bind to the GPR119 receptor and modulate its activity.
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