Invention Grant
US08809365B2 1-substituted 2-azabicyclo [3.1.1] heptyl derivatives useful as nicotinic acetylcholine receptor modulators for treating neurologic disorders
有权
用作治疗神经系统疾病的烟碱乙酰胆碱受体调节剂的1-取代的2-氮杂双环[3.1.1]庚基衍生物
![1-substituted 2-azabicyclo [3.1.1] heptyl derivatives useful as nicotinic acetylcholine receptor modulators for treating neurologic disorders](/docs/US/2014-08-19/US08809365B2/abs.jpg.600x600.jpg)
- Patent Title: 1-substituted 2-azabicyclo [3.1.1] heptyl derivatives useful as nicotinic acetylcholine receptor modulators for treating neurologic disorders
- Patent Title (中): 用作治疗神经系统疾病的烟碱乙酰胆碱受体调节剂的1-取代的2-氮杂双环[3.1.1]庚基衍生物
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Application No.: US13504618Application Date: 2010-11-03
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Publication No.: US08809365B2Publication Date: 2014-08-19
- Inventor: Christian Stevens , Ann De Blieck , Thomas Heugebaert
- Applicant: Christian Stevens , Ann De Blieck , Thomas Heugebaert
- Applicant Address: BE Ghent
- Assignee: Universiteit Gent
- Current Assignee: Universiteit Gent
- Current Assignee Address: BE Ghent
- Agency: Clark & Elbing LLP
- Priority: GB0919325.1 20091104
- International Application: PCT/EP2010/066764 WO 20101103
- International Announcement: WO2011/054885 WO 20110512
- Main IPC: A61K31/439
- IPC: A61K31/439 ; A61K31/403 ; C07D221/22 ; C07D487/04 ; C07D401/06 ; C07D401/12
![1-substituted 2-azabicyclo [3.1.1] heptyl derivatives useful as nicotinic acetylcholine receptor modulators for treating neurologic disorders](/abs-image/US/2014/08/19/US08809365B2/abs.jpg.150x150.jpg)
Abstract:
This invention provides 2-azabicyclo[3.1.1]heptyl derivatives, and methods for producing them, which are useful therapeutic agents for preventing or treating central nervous system disorders and disease mediated by a Nicotinic Acetylcholine Receptor such as, but not limited to, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy, dementia, pain and nicotine addiction.
Public/Granted literature
Information query
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