Invention Grant
- Patent Title: Deubiquitinase inhibitors and methods for use of the same
- Patent Title (中): 去泛素酶抑制剂及其使用方法
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Application No.: US13241802Application Date: 2011-09-23
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Publication No.: US08809377B2Publication Date: 2014-08-19
- Inventor: Nicholas J. Donato , Christiane Wobus , Hollis D. Showalter , Moshe Talpaz , Jeffrey W. Perry , Roderick J. Sorenson , Mary X. O'Riordan , Yafei Jin
- Applicant: Nicholas J. Donato , Christiane Wobus , Hollis D. Showalter , Moshe Talpaz , Jeffrey W. Perry , Roderick J. Sorenson , Mary X. O'Riordan , Yafei Jin
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: A61K31/444
- IPC: A61K31/444 ; A61K31/4433 ; A61K31/4436 ; A61K31/4439

Abstract:
Disclosed herein are methods of inhibiting a deubiquitinase (DUB), methods of treating pathogenic infections (e.g., viral, bacterial, and/or parasitic), methods of inhibiting cell proliferation, methods of treating a neurodegenerative disease, methods of treating one or more symptoms of a neurodegenerative disease or a genetic disorder, and compounds, wherein the compound can have a structure of formula (III):
Public/Granted literature
- US20120077806A1 Deubiquitinase Inhibitors and Methods for Use of the Same Public/Granted day:2012-03-29
Information query
IPC分类: