Invention Grant
- Patent Title: System and method for measuring the ratio of forward-propagating to back-propagating second harmonic-generation signal, and applications thereof
- Patent Title (中): 用于测量正向传播到后向传播的二次谐波发生信号的比率的系统和方法及其应用
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Application No.: US13696150Application Date: 2011-05-03
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Publication No.: US08812085B2Publication Date: 2014-08-19
- Inventor: Edward Brown, III , Xiaoxing Han
- Applicant: Edward Brown, III , Xiaoxing Han
- Applicant Address: US NY Rochester
- Assignee: University of Rochester
- Current Assignee: University of Rochester
- Current Assignee Address: US NY Rochester
- Agency: Bond, Schoeneck & King, PLLC
- Agent William Greener
- International Application: PCT/US2011/034921 WO 20110503
- International Announcement: WO2011/140030 WO 20111110
- Main IPC: A61B6/00
- IPC: A61B6/00
Abstract:
A method and system that enable the measurement of a second-harmonic-generation-forward/backward (SHG F/B) ratio from an object by performing only a single image scan using via epi-imaging using an epi-detection technique. Two simultaneous SGH images (a forward propagating SHG “F” image and a back propagating SHG “B” image) are generated during the single image scan. A pinhole mirror can be used to separate the F-SHG and the B-SHG, which are detected by separate detectors.
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