Embodiments of the present invention provide a cannulated screw driver assembly which includes a rigid guide pin such that the assembly can be used to assist the surgeon in inserting and positioning the rigid guide pin and an interference screw within a bone graft tunnel. Once the screw is properly placed, screw driver assembly components to include the rigid guide pin, the driver and the handle can be removed while the screw remains in the tunnel to secure the graft. In one embodiment, the interference screw can be removed from the distal end of the driver and the driver and handle can be removed from the screw's proximal end. Embodiments of the inventions also include an interchangeable driver to mate with different size and types of interference screws.