Invention Grant
- Patent Title: Radioactive metal-labeled anti-cadherin antibody
- Patent Title (中): 放射性金属标记的抗钙粘蛋白抗体
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Application No.: US13578462Application Date: 2011-02-09
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Publication No.: US08815211B2Publication Date: 2014-08-26
- Inventor: Akihiro Hino , Akio Nagano , Masahiko Watanabe , Tadasi Matsuura , Hirokazu Satoh , Fumiko Nomura , Katsuyuki Mitomo
- Applicant: Akihiro Hino , Akio Nagano , Masahiko Watanabe , Tadasi Matsuura , Hirokazu Satoh , Fumiko Nomura , Katsuyuki Mitomo
- Applicant Address: JP Tokyo JP Tokyo
- Assignee: Fujifilm RI Pharma Co., Ltd.,Perseus Proteomics Inc.
- Current Assignee: Fujifilm RI Pharma Co., Ltd.,Perseus Proteomics Inc.
- Current Assignee Address: JP Tokyo JP Tokyo
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- International Application: PCT/JP2011/052759 WO 20110209
- International Announcement: WO2011/099524 WO 20110818
- Main IPC: A61K49/00
- IPC: A61K49/00 ; A61K39/395 ; C07K16/00 ; C07K16/28
Abstract:
An object of the present invention is to provide a radioactive metal anti-cadherin antibody which is highly accumulated specifically in cancer tissue. Another object is to provide a cancer therapeutic agent having high anti-cancer effect and safety and a cancer diagnostic agent. The radioactive metal-labeled anti-cadherin antibody is obtained by binding a radioactive metallic element to an anti-cadherin antibody via a metal-chelating reagent.
Public/Granted literature
- US20130071324A1 RADIOACTIVE METAL-LABELED ANTI-CADHERIN ANTIBODY Public/Granted day:2013-03-21
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