Invention Grant
US08815213B2 RGD-(bacterio)chlorophyll conjugates for photodynamic therapy and Imaging of Necrotic tumors
有权
RGD-（细菌）叶绿素共轭物用于光动力学治疗和坏死肿瘤成像
- Patent Title: RGD-(bacterio)chlorophyll conjugates for photodynamic therapy and Imaging of Necrotic tumors
- Patent Title (中): RGD-（细菌）叶绿素共轭物用于光动力学治疗和坏死肿瘤成像
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Application No.: US12920088Application Date: 2009-03-01
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Publication No.: US08815213B2Publication Date: 2014-08-26
- Inventor: Avigdor Scherz , Liat Goldshaid , Yoram Salomon
- Applicant: Avigdor Scherz , Liat Goldshaid , Yoram Salomon
- Applicant Address: IL Rehovot
- Assignee: Yeda Research and Development Co. Ltd.
- Current Assignee: Yeda Research and Development Co. Ltd.
- Current Assignee Address: IL Rehovot
- Agency: Browdy and Neimark, PLLC
- International Application: PCT/IL2009/000228 WO 20090301
- International Announcement: WO2009/107139 WO 20090903
- Main IPC: A61B5/055
- IPC: A61B5/055 ; A61K51/04 ; A61K41/00 ; C07D257/04
Abstract:
RGD-chlorophyll and RGD-bacteriochlorophyll conjugates that home and accumulate in necrotic tumor domains much longer than in tumor non-necrotic domains are provided for use in minimally invasive tumor-targeted imaging, tumor-targeted photodynamic therapy, and/or on-line prognosis of necrotic tumors.
Public/Granted literature
- US20110064658A1 RGD-(bacterio)chlorophyll conjugates for photodynamic therapy and Imaging of Necrotic tumors Public/Granted day:2011-03-17
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