Invention Grant
- Patent Title: Methods and agents for the diagnosis and treatment of hepatocellular carcinoma
- Patent Title (中): 肝细胞癌诊断和治疗的方法和药剂
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Application No.: US12933248Application Date: 2009-03-18
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Publication No.: US08815240B2Publication Date: 2014-08-26
- Inventor: Kuo-Jang Kao , Andrew T. Huang
- Applicant: Kuo-Jang Kao , Andrew T. Huang
- Applicant Address: TW Taipei
- Assignee: China Synthetic Rubber Corporation
- Current Assignee: China Synthetic Rubber Corporation
- Current Assignee Address: TW Taipei
- Agency: Hamilton, Brook, Smith & Reynolds, P.C.
- International Application: PCT/US2009/001689 WO 20090318
- International Announcement: WO2009/117096 WO 20090924
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; C12P21/08 ; C12N5/12

Abstract:
The present invention relates to methods of diagnosing, and methods of treating, hepatocellular carcinoma in a subject. The invention also relates to antagonists of PLVAP proteins, such as antibodies that specifically bind PLVAP proteins, as well as compositions and kits comprising antagonists of PLVAP proteins. The invention further relates to humanized antibodies that specifically bind PLVAP protein.
Public/Granted literature
- US20110085973A1 Methods and Agents for the Diagnosis and Treatment of Hepatocellular Carcinoma Public/Granted day:2011-04-14
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