Invention Grant
- Patent Title: Avian derived antibodies
- Patent Title (中): 禽源性抗体
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Application No.: US12800989Application Date: 2010-05-27
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Publication No.: US08815242B2Publication Date: 2014-08-26
- Inventor: Alex J. Harvey
- Applicant: Alex J. Harvey
- Applicant Address: US MA Lexington
- Assignee: Synageva BioPharma Corp.
- Current Assignee: Synageva BioPharma Corp.
- Current Assignee Address: US MA Lexington
- Agent Hak J. Chang
- Main IPC: C07K16/02
- IPC: C07K16/02 ; C07K16/28 ; C07K16/30 ; A61K39/395 ; A01K67/027 ; C12N15/85
Abstract:
The invention is drawn to a composition comprising an isolated mixture of cytotoxic anti-CD20 antibody molecules produced in a transgenic avian. The antibody molecules have a heavy chain and a light chain whose amino acid sequences set forth in SEQ ID NOs: 4 and 5 and exhibit an increased level of cytotoxicity as compared to anti-CD20 antibody molecules produced in CHO cells.
Public/Granted literature
- US20100303806A1 Avian derivedantibodies Public/Granted day:2010-12-02
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