Invention Grant
- Patent Title: Method for production of pH stable enveloped viruses
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Application No.: US13129806Application Date: 2009-11-25
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Publication No.: US08815252B2Publication Date: 2014-08-26
- Inventor: Julia Romanova , Andrej Egorov , Brigitte Krenn , Markus Wolschek , Sabine Nakowitsch
- Applicant: Julia Romanova , Andrej Egorov , Brigitte Krenn , Markus Wolschek , Sabine Nakowitsch
- Applicant Address: CH Glattpark (Opfikon)
- Assignee: Baxter Healthcare SA
- Current Assignee: Baxter Healthcare SA
- Current Assignee Address: CH Glattpark (Opfikon)
- Agency: Loza & Loza, LLP
- Agent Michael Fedrick
- Priority: EP09153664 20090225
- International Application: PCT/EP2009/065812 WO 20091125
- International Announcement: WO2010/060921 WO 20100603
- Main IPC: A61K39/145
- IPC: A61K39/145 ; C12N7/00 ; C12N7/08
Abstract:
The present invention provides a method for producing pH-stable enveloped viruses wherein said viruses are used for infection of host cells under low pH conditions and for incubation with cell culture cells under conditions of low pH, as well as influenza viruses obtainable by this method which exhibit a high growth rate in cell culture, increased pH and temperature stability and which have human receptor specificity.
Public/Granted literature
- US20110223199A1 METHOD FOR PRODUCTION OF pH STABLE ENVELOPED VIRUSES Public/Granted day:2011-09-15
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