Invention Grant
- Patent Title: Tandem facial amphiphiles
- Patent Title (中): 串联面部两亲物
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Application No.: US13669198Application Date: 2012-11-05
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Publication No.: US08815263B2Publication Date: 2014-08-26
- Inventor: Pil Seok Chae , Samuel Helmer Gellman
- Applicant: Wisconsin Alumni Research Foundation
- Applicant Address: US WI Madison
- Assignee: Wisconsin Alumni Research Foundation
- Current Assignee: Wisconsin Alumni Research Foundation
- Current Assignee Address: US WI Madison
- Agency: DeWitt Ross & Stevens SC
- Agent Joseph T. Leone, Esq.; Daniel A. Blasiole
- Main IPC: A61K9/00
- IPC: A61K9/00 ; C07K1/00 ; A23J1/00 ; C07J41/00
Abstract:
The invention provides tandem facial amphiphiles for biochemical manipulations and characterization of membrane proteins, such as intrinsic membrane proteins. Members of this new family display favorable behavior with several membrane proteins. These amphiphiles can form relatively small micelles, and small changes in amphiphile chemical structures can result in large changes in their physical properties. The tandem facial amphiphiles can be used to aid the solubilization, isolation, purification, stabilization, crystallization, and/or structural determination of membrane proteins.
Public/Granted literature
- US20130115251A1 TANDEM FACIAL AMPHIPHILES Public/Granted day:2013-05-09
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