Invention Grant
US08815582B2 Mammalian cell expressing Volvox carteri light-activated ion channel protein (VChR1)
有权
哺乳动物细胞表达Volvox carteri光激活离子通道蛋白（VChR1）
- Patent Title: Mammalian cell expressing Volvox carteri light-activated ion channel protein (VChR1)
- Patent Title (中): 哺乳动物细胞表达Volvox carteri光激活离子通道蛋白（VChR1）
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Application No.: US13718243Application Date: 2012-12-18
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Publication No.: US08815582B2Publication Date: 2014-08-26
- Inventor: Karl Deisseroth , Feng Zhang , Viviana Gradinaru
- Applicant: The Board of Trustees of the Leland Stanford Junior University
- Applicant Address: US CA Palo Alto
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Palo Alto
- Agency: Bozicevic, Field & Francis LLP
- Agent Paula A. Borden
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02 ; C12N15/00 ; C07K14/47 ; C07K14/405
Abstract:
Methods, systems and devices are implemented in connection with light-responsive ion channel molecules. One such method is implemented using a light-activated ion channel molecule that responds to a light stimulus. The method includes engineering the light-activated ion channel molecule in a cell; and activating the ion channel molecule, in response to light stimulus that is provided to the ion channel molecule and that has properties that do not activate a ChR2 ion channel, to allow ions to pass through the light-activated ion channel molecule.
Public/Granted literature
- US20130244323A1 Systems, Methods and Compositions for Optical Stimulation of Target Cells Public/Granted day:2013-09-19
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