Invention Grant
- Patent Title: Methods and compositions related to dopaminergic neuronal cells
- Patent Title (中): 与多巴胺能神经元细胞相关的方法和组合
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Application No.: US13696775Application Date: 2011-04-20
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Publication No.: US08815592B2Publication Date: 2014-08-26
- Inventor: Karl-Heinz Krause , Olivier Preynat-Seauve
- Applicant: Karl-Heinz Krause , Olivier Preynat-Seauve
- Applicant Address: US NV Carson City
- Assignee: Research Development Foundation
- Current Assignee: Research Development Foundation
- Current Assignee Address: US NV Carson City
- Agency: Parker Highlander PLLC
- International Application: PCT/US2011/033232 WO 20110420
- International Announcement: WO2011/133661 WO 20111027
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02 ; C07D263/58 ; C07D235/26 ; A61K35/30 ; A61K31/4184 ; A61K31/423 ; C12N5/0793

Abstract:
A method of differentiation stem cells cells by contacting stem cells with a dopaminergic differentiation agent is provided in certain aspects. For example, the agent may comprise substituted benzoxazole. These methods and compositions may be used in toxicological screens, e.g., to evaluate the neurotoxicity of a test compound or treatment of neurological disorders.
Public/Granted literature
- US20130149717A1 METHODS AND COMPOSITIONS RELATED TO DOPAMINERGIC NEURONAL CELLS Public/Granted day:2013-06-13
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