Invention Grant
US08815825B2 Methods and compositions for the specific inhibition of beta-catenin by double-stranded RNA
有权
通过双链RNA特异性抑制β-连环蛋白的方法和组合物
- Patent Title: Methods and compositions for the specific inhibition of beta-catenin by double-stranded RNA
- Patent Title (中): 通过双链RNA特异性抑制β-连环蛋白的方法和组合物
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Application No.: US13718525Application Date: 2012-12-18
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Publication No.: US08815825B2Publication Date: 2014-08-26
- Inventor: Bob D. Brown , Henryk T. Dudek
- Applicant: Dicerna Pharmaceuticals, Inc.
- Applicant Address: US MA Watertown
- Assignee: Dicerna Pharmaceuticals, Inc.
- Current Assignee: Dicerna Pharmaceuticals, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Edwards Wildman Palmer LLP
- Agent Christopher R. Cowles
- Main IPC: C12N15/11
- IPC: C12N15/11
Abstract:
This invention relates to compounds, compositions, and methods useful for reducing β-catenin target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate siRNA (DsiRNA) agents.
Public/Granted literature
- US20130109740A1 METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF BETA-CATENIN BY DOUBLE-STRANDED RNA Public/Granted day:2013-05-02
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