Invention Grant
US08815839B2 Heteroaromatic and aromatic piperazinyl azetidinyl amides as monoacylglycerol lipase inhibitors
有权
作为单酰基甘油脂肪酶抑制剂的杂芳族和芳族哌嗪基氮杂环丁烷基酰胺
- Patent Title: Heteroaromatic and aromatic piperazinyl azetidinyl amides as monoacylglycerol lipase inhibitors
- Patent Title (中): 作为单酰基甘油脂肪酶抑制剂的杂芳族和芳族哌嗪基氮杂环丁烷基酰胺
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Application No.: US13784036Application Date: 2013-03-04
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Publication No.: US08815839B2Publication Date: 2014-08-26
- Inventor: Kristen Chevalier , Jose Clemente , Scott L Dax , Chris Flores , Li Liu , Mark J Macielag , Mark McDonnell , Marina Nelen , Erica Nulton , Stephen Prouty , Matthew Todd , Sui-Po Zhang , Bin Zhu
- Applicant: Janssen Pharmaceutica, NV
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica, NV
- Current Assignee: Janssen Pharmaceutica, NV
- Current Assignee Address: BE
- Agent Thomas J. Dodd
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K31/551 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D417/12
Abstract:
Disclosed are compounds, compositions and methods for treating diseases, syndromes, conditions and disorders that are affected by the inhibition of MGL, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, r, R2 and Z are defined herein.
Public/Granted literature
- US20130184251A1 HETEROAROMATIC AND AROMATIC PIPERAZINYL AZETIDINYL AMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS Public/Granted day:2013-07-18
Information query
IPC分类:
