Invention Grant
![Imidazo [2, 1-B] [1, 3, 4] thiadiazole derivatives](/docs/US/2014-08-26/US08815918B2/abs.jpg.600x600.jpg)
- Patent Title: Imidazo [2, 1-B] [1, 3, 4] thiadiazole derivatives
- Patent Title (中): 咪唑并[2,1-B] [1,3,4]噻二唑衍生物
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Application No.: US13262183Application Date: 2010-04-01
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Publication No.: US08815918B2Publication Date: 2014-08-26
- Inventor: Joaquin Pastor Fernández , Guido Kurz , Sonia Martinez Gonzalez
- Applicant: Joaquin Pastor Fernández , Guido Kurz , Sonia Martinez Gonzalez
- Applicant Address: ES Madrid
- Assignee: Centro Nacional de Investigaciones Oncologicas (CNIO)
- Current Assignee: Centro Nacional de Investigaciones Oncologicas (CNIO)
- Current Assignee Address: ES Madrid
- Agency: McCarter & English, LLP
- Agent Steven G. Davis
- Priority: EP9380069 20090402
- International Application: PCT/GB2010/000674 WO 20100401
- International Announcement: WO2010/112874 WO 20101007
- Main IPC: A61K31/433
- IPC: A61K31/433 ; A61K31/4188 ; C07D285/02 ; C07D235/00
![Imidazo [2, 1-B] [1, 3, 4] thiadiazole derivatives](/abs-image/US/2014/08/26/US08815918B2/abs.jpg.150x150.jpg)
Abstract:
There is provided compounds of formula (I): wherein R1, R2 and R3 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. PI3-K, particularly class I PI3K) is desired and/or required, and particularly in the treatment of cancer.
Public/Granted literature
- US20120094996A1 Imidazo [2, 1-B] [1, 3, 4] Thiadiazole Derivatives Public/Granted day:2012-04-19
Information query
