Invention Grant
- Patent Title: Induction of alpha helix conformations in proteins and peptides
- Patent Title (中): 诱导蛋白质和肽中的α螺旋构象
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Application No.: US13383266Application Date: 2010-07-09
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Publication No.: US08815932B2Publication Date: 2014-08-26
- Inventor: Hans-Günther Schmalz , Ronald Kuhne , Verena Hack , Cédric Reuter
- Applicant: Hans-Günther Schmalz , Ronald Kuhne , Verena Hack , Cédric Reuter
- Applicant Address: DE Köln DE Berlin
- Assignee: Universität zu Köln,Forschungsverbund Berlin E. V.
- Current Assignee: Universität zu Köln,Forschungsverbund Berlin E. V.
- Current Assignee Address: DE Köln DE Berlin
- Agency: Norris McLaughlin & Marcus, P.A.
- Priority: DE102009032902 20090710
- International Application: PCT/EP2010/004213 WO 20100709
- International Announcement: WO2011/003626 WO 20110113
- Main IPC: C07D487/18
- IPC: C07D487/18 ; A61K31/407
Abstract:
Substituted tricyclic diproline analogues of the formula (I): wherein the variables are as defined herein. Also disclosed are methods for the production thereof, the use thereof for the induction of an alpha-helix conformation in peptides and/or proteins, pharmaceuticals containing said compounds, methods for the production of a peptide library containing said compounds, and peptide libraries containing said compounds.
Public/Granted literature
- US20120172402A1 INDUCTION OF ALPHA HELIX CONFORMATIONS IN PROTEINS AND PEPTIDES Public/Granted day:2012-07-05
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