Invention Grant
US08815933B2 Treatment of cognitive disorders with (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof
有权
用（R）-7-氯-N-（奎宁环-3-基）苯并[b]噻吩-2-甲酰胺及其药学上可接受的盐治疗认知障碍
![Treatment of cognitive disorders with (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof](/docs/US/2014-08-26/US08815933B2/abs.jpg.600x600.jpg)
- Patent Title: Treatment of cognitive disorders with (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof
- Patent Title (中): 用（R）-7-氯-N-（奎宁环-3-基）苯并[b]噻吩-2-甲酰胺及其药学上可接受的盐治疗认知障碍
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Application No.: US14175654Application Date: 2014-02-07
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Publication No.: US08815933B2Publication Date: 2014-08-26
- Inventor: Richard Chesworth , Gideon Shapiro , Gerhard Koenig
- Applicant: EnVivo Pharmaceuticals, Inc.
- Applicant Address: US MA Watertown
- Assignee: Forum Pharmaceuticals, Inc.
- Current Assignee: Forum Pharmaceuticals, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Jones Day
- Main IPC: A61K31/403
- IPC: A61K31/403 ; C07D487/02 ; A61K31/439
![Treatment of cognitive disorders with (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof](/abs-image/US/2014/08/26/US08815933B2/abs.jpg.150x150.jpg)
Abstract:
(R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide has been found to have procognitive effects in humans at unexpectedly low doses. Thus, (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof can be used at unexpectedly low doses to improve cognition.
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